The hybridoma line OX-23 was raised by immunizing BALB/c mice with Factor H and fusion of spleen cells with NS0 mouse myeloma cells. The antibody was shown to detect human complement control protein, Factor H. OX-23, also known as MRC OX-23, reduced the increase in cofactor activity observed in the presence of OX-24 (Sigma Catalogue no. 00010403). It was reported that OX-23 and OX-24 react with different epitopes on the Factor H molecule.
Maintain cultures between 3-9 x 100,000 cells/ml; 5% CO2; 37°C.
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Clause de non-responsabilité
This cell line has special release conditions: Commercial organisations are required to complete the ′Cell Line Release Authorisation for Research Use in Commercial Organisations′ release conditions form.
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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The complement system is important in immunosurveillance against tumors. However, malignant cells are usually resistant to complement-mediated lysis. In this study, we examine the expression of factor H, an inhibitor of complement activation, and factor H-like protein 1 (FHL-1), its
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