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Principaux documents

B1160000

Bupivacaine hydrochloride

European Pharmacopoeia (EP) Reference Standard

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About This Item

Formule empirique (notation de Hill) :
C18H28N2O · HCl
Numéro CAS:
18010-40-7
Poids moléculaire :
324.89
Numéro MDL:
MFCD00078956
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Qualité

pharmaceutical primary standard

Famille d'API

bupivacaine

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

[Cl-].[N+H]1(C(CCCC1)C(=O)Nc2c(cccc2C)C)CCCC

InChI

1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H

Clé InChI

SIEYLFHKZGLBNX-UHFFFAOYSA-N

Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bupivacaine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1078507

Bupivacaine hydrochloride, United States Pharmacopeia (USP) Reference Standard

Y0000088

Bupivacaine impurity B, European Pharmacopoeia (EP) Reference Standard

Y0000089

Bupivacaine impurity E, European Pharmacopoeia (EP) Reference Standard

Y0001575

2,6-Dimethylaniline, European Pharmacopoeia (EP) Reference Standard

1078529

Bupivacaine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1078518

Bupivacaine Related Compound A, United States Pharmacopeia (USP) Reference Standard

PHR1738

Bupivacaine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1756

Bupivacaine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

BP479

Bupivacaine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR9084

(S)-Bupivacaine, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9147

N-(2,6-Dimethylphenyl)pyridine-2-carboxamide, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H300 + H310 + H330

Classification des risques

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Sigma-Aldrich

SML1444

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Qing-he Zhou et al.
Anesthesia and analgesia, 119(1), 203-206 (2014-05-09)
The spread of spinal anesthesia is highly unpredictable. In patients with increased abdominal girth and short stature, a greater cephalad spread after a fixed amount of subarachnoidally administered plain bupivacaine is often observed. We hypothesized that there is a strong
Michael R Fettiplace et al.
Anesthesiology, 120(4), 915-925 (2014-02-06)
Recent publications have questioned the validity of the "lipid sink" theory of lipid resuscitation while others have identified sink-independent effects and posed alternative mechanisms such as hemodilution. To address these issues, the authors tested the dose-dependent response to intravenous lipid
Ting Li et al.
International journal of molecular sciences, 20(17) (2019-09-06)
The G-protein-coupled receptor (GPCR) regulated intracellular signaling pathway is known to be involved in the development of insecticide resistance in the mosquito, Culex quinquefasciatus. To elucidate the specific role of each effector in the GPCR regulating pathway, we initially expressed
David R Walega et al.
Journal of oral & facial pain and headache, 28(2), 171-175 (2014-05-14)
Burning Mouth Syndrome (BMS) is a chronic painful disorder characterized by unremitting bilateral burning oral pain often associated with taste abnormalities and complaints of dry mouth. The diagnosis is made by history and symptom presentation in the absence of an
David Buck et al.
Anesthesia and analgesia, 119(1), 137-140 (2014-06-20)
An otherwise healthy 11-month-old, 8-kg infant presented for an elective circumcision. After a penile block with an excessive dose of 0.5% bupivacaine, the patient progressed to ventricular tachycardia. He was resuscitated with intralipid and had an uneventful recovery. The case
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