32481

Halofuginone hydrobromide

VETRANAL^®, analytical standard

• Synonyme(s) : trans-(±)-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4(3H)-quinazolinone monohydrobromide
• Formule empirique (notation de Hill) : C₁₆H₁₇BrClN₃O₃ · HBr
• Numéro CAS: 64924-67-0
• Poids moléculaire : 495.59
• Numéro MDL: MFCD23843776
• Code UNSPSC : 41116107
• ID de substance PubChem : 329754239
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Gamme de produits: VETRANAL^®
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): forensics and toxicology; pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: Br.O[C@@H]1CCCN[C@H]1CC(=O)CN2C=Nc3cc(Br)c(Cl)cc3C2=O
• InChI: 1S/C16H17BrClN3O3.BrH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/m0./s1
• Clé InChI: SJUWEPZBTXEUMU-LDXVYITESA-N

Description

Description générale

Halofuginone hydrobromide is a synthetic alkaloid derivative of febrifugine, used widely against coccidiosis in the poultry sector. It′s a specific collagen Type I inhibitor that antagonizes or inhibits the development of new blood vessels and hence can prevent intimal hyperplasia at a vascular anastomosis. [1][2]

Application

The analytical standard can be used as follows:

• Multi-residue analysis of 11 coccidiostats in 60 feed samples by reversed phase-high performance liquid chromatography (RP-HPLC) combined with tandem mass spectrometry (MS/MS)
• Simultaneous determination of 15 allowed and banned coccidiostats in animal feed samples by liquid chromatography-tandem mass spectrometry method (LC-MS/MS)
• UHPLC-MS/MS method-based detection and measurement of 26 anticoccidials in surface and groundwater samples following their solid phase extraction (SPE)
• Analysis of 48 anti-microbial compounds in pig feed samples using LC combined with high-resolution mass spectrometry (HRMS)(4)Development of an LC-MS/MS method to determine 20 coccidiostats in different animal muscle samples

Autres remarques

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H310 + H330,H315,H319,H410
• Conseils de prudence: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Classification des risques: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable