8.51028

Bis-Boc-amino-oxyacetic acid

Novabiochem^®

• Synonyme(s) : Bis-Boc-amino-oxyacetic acid, Boc ₂-Aoa-OH
• Formule empirique (notation de Hill): C₁₂H₂₁NO₇ · xH₂O
• Poids moléculaire : 291.30 (anhydrous basis)
• Code UNSPSC : 12352209
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Gamme de produits: Novabiochem^®
• Pureté: ≥97% (TLC)
• Forme: powder
• Pertinence de la réaction: reagent type: ligand
• Fabricant/nom de marque: Novabiochem^®
• Application(s): peptide synthesis
• Température de stockage: 2-8°C

Description

Description générale

This reagent can be used to introduce a hydroxylamine functionality to N-terminal or side-chain amino groups. Hydroxylamine-labeled peptides prepared in this manner can be ligated in aqueous solution at pH 3.5 to aldehyde-containing peptides via oxime formation. This bis-protected derivative eliminates oligomer formation which can occur with mono-protected hydroxylamine reagents as a result of double acylation. Coupling of this derivative should be done using an OSu ester.

Literature references

^[1] J. C. Spetzler & T. Hoeg-Jensen (2001) J. Peptide Sci., 7, 537.

Liaison

Replaces: 01-63-0129

Remarque sur l'analyse

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 97 %
Water (K. F.): 3.0 - 8.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3