890890C

18:1 TAP (DOTAP)

Avanti Research^™ - A Croda Brand

• Synonyme(s) : 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)
• Formule empirique (notation de Hill): C₄₂H₈₀NO₄Cl
• Numéro CAS: 132172-61-3
• Poids moléculaire : 698.54
• Numéro MDL: MFCD01310872
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Forme: liquid
• Conditionnement: pkg of 1 × 2.5 mL (890890C-25mg); pkg of 2 × 20 mL (890890C-1g); pkg of 2 × 4 mL (890890C-200mg); pkg of 5 × 4 mL (890890C-500mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand
• Concentration: 10 mg/mL (890890C-25mg); 25 mg/mL (890890C-1g); 25 mg/mL (890890C-200mg); 25 mg/mL (890890C-500mg)
• Application(s): advanced drug delivery
• Type de lipide: cationic lipids; transfection
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Cl-]
• InChI: 1S/C42H80NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,40H,6-19,24-39H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;
• Clé InChI: KSXTUUUQYQYKCR-LQDDAWAPSA-M

Description

Application

18:1 TAP (DOTAP) has been used in the preparation of liposome-supported bilayers.[1]

Actions biochimiques/physiologiques

18:1 TAP (DOTAP) is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery.[2] The lipid composition and cell type affects the transfection potential of DOTAP(1,2-dioleoyl-3-trimethylammonium-propane).[3] 18:1 TAP (DOTAP) mediates gene knockdown technique in hematopoietic stem cells (HSCs).[4]

Conditionnement

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (890890C-1g)

5 mL Clear Glass Sealed Ampule (890890C-200mg)

5 mL Clear Glass Sealed Ampule (890890C-25mg)

5 mL Clear Glass Sealed Ampule (890890C-500mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Conseils de prudence: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organes cibles: Central nervous system, Liver,Kidney
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable