850355C

16:0 PC (DPPC)

Avanti Research^™ - A Croda Brand

• Synonyme(s) : 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine; DPPC; PC(16:0/16:0)
• Formule empirique (notation de Hill): C₄₀H₈₀NO₈P
• Numéro CAS: 63-89-8
• Poids moléculaire : 734.04
• Numéro MDL: MFCD00066101
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Description: 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, chloroform
• Essai: >99% (TLC)
• Forme: liquid
• Conditionnement: pkg of 1 × 2.5 mL (850355C-25mg); pkg of 1 × 20 mL (850355C-500mg); pkg of 2 × 20 mL (850355C-1g); pkg of 2 × 4 mL (850355C-200mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand
• Concentration: 10 mg/mL (850355C-25mg); 25 mg/mL (850355C-1g); 25 mg/mL (850355C-200mg); 25 mg/mL (850355C-500mg)
• Type de lipide: cardiolipins; phospholipids
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [P](=O)([O-])(OCC[N+](C)(C)C)OCC(OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCC
• InChI: 1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3
• Clé InChI: KILNVBDSWZSGLL-UHFFFAOYSA-N

Description

Description générale

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes.[1] It is also an important component of the mucosal layer of the colon.[2]

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

16:0 PC (DPPC) is suitable for use:

• in vesicle preparation[3][4]
• as the main phospholipid component for all ultrasound contrast agents (UCA) formulations[5]
• as a component for microbubble preparation[6]
• in the preparation of lipid bilayers[7]

Actions biochimiques/physiologiques

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.[2] It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.[8]

Conditionnement

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850355C-1g)

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850355C-500mg)

5 mL Clear Glass Sealed Ampule (850355C-200mg)

5 mL Clear Glass Sealed Ampule (850355C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Conseils de prudence: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organes cibles: Central nervous system, Liver,Kidney
• Code de la classe de stockage: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable