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Merck
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379506

Sigma-Aldrich

Tris(2,3-epoxypropyl) isocyanurate

Synonyme(s) :

1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione, TGIC, Triglycidyl isocyanurate

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About This Item

Formule empirique (notation de Hill) :
C12H15N3O6
Numéro CAS:
Poids moléculaire :
297.26
Numéro CE :
Numéro MDL:
Code UNSPSC :
12162002
ID de substance PubChem :
Nomenclature NACRES :
NA.23
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Forme

powder

Chaîne SMILES 

O=C1N(CC2CO2)C(=O)N(CC3CO3)C(=O)N1CC4CO4

InChI

1S/C12H15N3O6/c16-10-13(1-7-4-19-7)11(17)15(3-9-6-21-9)12(18)14(10)2-8-5-20-8/h7-9H,1-6H2

Clé InChI

OUPZKGBUJRBPGC-UHFFFAOYSA-N

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Pictogrammes

Skull and crossbonesHealth hazardCorrosion

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Muta. 1B - Skin Sens. 1 - STOT RE 2

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Jing-Ping Wang et al.
Toxicology and applied pharmacology, 273(1), 110-120 (2013-08-21)
In this work, we demonstrated that the growth of human non-small-cell-lung-cancer cells H460 and A549 cells can be inhibited by low concentrations of an epoxide derivative, teroxirone, in both in vitro and in vivo models. The cytotoxicity was mediated by
P Dombernowsky et al.
Cancer chemotherapy and pharmacology, 11(1), 59-61 (1983-01-01)
alpha-1,3,5-Triglycidyl-s-triazinetrione (TGT) is a triepoxide derivative with alkylating properties discovered by random screening. TGT has been found to be active against a wide variety of murine tumors, including a P388 subline resistant to cyclophosphamide. The starting dose in this phase-I
G Atassi et al.
Cancer treatment reviews, 11 Suppl A, 99-110 (1984-03-01)
As a follow-up to our initial results on the antineoplastic activity of alpha-1,3,5-triglycidyl-s-triazinetrione (alpha TGT, NSC-296934, Teroxirone), many new epoxyde derivatives were tested against murine tumours, mostly against P388 leukaemia, to determine their antineoplastic role and to characterize their specific
Occupational contact dermatitis from triglycidyl isocyanurate in a powder paint factory.
C S Munro et al.
Contact dermatitis, 26(1), 59-59 (1992-01-01)
Occupational contact dermatitis from triglycidyl isocyanurate in a powder paint sprayer.
J P McFadden et al.
Contact dermatitis, 28(4), 251-251 (1993-04-01)

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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