- Transition-metal-free atropo-selective synthesis of biaryl compounds based on arynes.
Transition-metal-free atropo-selective synthesis of biaryl compounds based on arynes.
Chemistry (Weinheim an der Bergstrasse, Germany) (2012-09-29)
Frédéric R Leroux, Anaïs Berthelot, Laurence Bonnafoux, Armen Panossian, Françoise Colobert
PMID23019081
ZUSAMMENFASSUNG
A modular way towards biaryls: Highly enantioenriched biphenyls can be prepared based on a transition-metal-free aryl-aryl coupling followed by efficient desymmetrization or deracemization and chemoselective functionalization (see scheme).