1027302

Amiodaron -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): (2-Butyl-3-benzofuranyl)-[4-(2-diethylamino-ethoxy)-3,5-diiodphenyl]-keton -hydrochlorid, (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)-ethoxy]-3,5-diiod-phenyl]-methanon -hydrochlorid
• Empirische Formel (Hill-System): C₂₅H₂₉I₂NO₃ · HCl
• CAS-Nummer: 19774-82-4
• Molekulargewicht: 681.77
• NACRES: NA.24
• PubChem Substance ID: 329748999
• UNSPSC Code: 41116107
• MDL number: MFCD00069204

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: amiodarone
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: C(=O)(C=1C=2C(OC1CCCC)=CC=CC2)C3=CC(I)=C(OCCN(CC)CC)C(I)=C3.Cl
• InChI: 1S/C25H29I2NO3.ClH/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3;/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;1H
• InChI key: ITPDYQOUSLNIHG-UHFFFAOYSA-N

Beschreibung

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amiodarone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Amiodarone Hydrochloride Compounded Oral Suspension
• Amiodarone Hydrochloride Injection
• Amiodarone Hydrochloride Tablets

Biochem/physiol Actions

Non-selective ion channel blocker. Amiodarone induces an immediate influx of Ca²⁺ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H315,H319,H335,H351,H361fd,H362,H410
• pcodes: P260 - P263 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Lact. - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable