T113

3-Tropanylindole-3-carboxylate methiodide

solid

• Synonym(e): ICS-205,930 methiodide
• Empirische Formel (Hill-System): C₁₈H₂₃IN₂O₂
• CAS-Nummer: 115626-53-4
• Molekulargewicht: 426.29
• MDL-Nummer: MFCD00210222
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278764

Eigenschaften

• Form: solid
• Farbe: white
• Löslichkeit: H₂O: soluble; ethanol: soluble
• Lagertemp.: −20°C
• SMILES String: [I-].C[N+]1(C)C2CCC1CC(C2)OC(=O)c3c[nH]c4ccccc34
• Angaben zum Gen: human ... HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242)

Beschreibung

Anwendung

3-Tropanylindole-3-carboxylate methiodide was used to study the role of 5-HT₃ receptor-mediated cell signaling in mouse interstitial cells of Cajal and in cocaine-induced aggressive behavior in hamsters.

Biochem./physiol. Wirkung

3-Tropanylindole-3-carboxylate methiodide is an antagonist of 5-HT₃ receptor that has antiemetic effects. It modulates the pacemaker activities of the mouse small intestine cells. It regulates the aggressive behavior induced by cocaine in hamsters.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)