SRP8021

NMNAT1 human

recombinant, expressed in E. coli, His tagged, >95% (SDS-PAGE)

• Synonym(e): EC 2.7.7.1, IL-1F9, NMN adenylyltransferase 1, Nicotinamide mononucleotide adenylyltransferase 1
• CAS-Nummer: 2230771-74-9
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Markierung: His tagged
• Assay: >95% (SDS-PAGE)
• Form: liquid
• Mol-Gew.: monomer ~33.3 kDa
• Verpackung: pkg of 10 μg
• Konzentration: ≥0.2 mg/mL
• Farbe: clear
• UniProt-Hinterlegungsnummer: Q9HAN9
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... NMNAT1(64802)

Beschreibung

Allgemeine Beschreibung

Nuclear NMNAT isoform. Catalyzes the formation of NAD⁺ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.

Physikalische Form

Solution in 50 mM sodium phosphate, pH 8.0, containing 300 mM sodium chloride, 2 mM DTT and 10% glycerol.

Sonstige Hinweise

Human full-length NMNAT1 (aa 1-279) is fused at the N-terminus to a His-tag.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable