SRP5115

P73g, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Synonym(e): TAp73γ, TP73
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Rekombinant: expressed in baculovirus infected Sf9 cells
• Assay: ≥70% (SDS-PAGE)
• Form: buffered aqueous glycerol solution
• Mol-Gew.: ~85 kDa
• NCBI-Hinterlegungsnummer: O15350-3
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... TP73(7161)

Beschreibung

Allgemeine Beschreibung

p73γ is a member of the p53 family of transcription factors which are involved in cellular responses to stress and development. There are four isoforms of p73 (p73α, p73β, p73δ and p73γ) which differed in their abilities to form homodimeric and heterodimeric interactions with each other and with p53. The p73 isoforms also differed in their abilities to activate transcription of the p21(Waf1) promoter and to inhibit colony formation. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. p73 is a stress-response gene that activates transcription of p53-responsive genes and inhibits cell growth in a p53-like manner by inducing apoptosis.

Physikalische Form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Angaben zur Herstellung

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable