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Merck

SRP3104

Sigma-Aldrich

LD78 Beta Peptide

≥98% (HPLC), human recombinant, expressed in E. coli, suitable for cell culture

Synonym(e):

CCL3L1

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About This Item

UNSPSC-Code:
12352202
NACRES:
NA.32

product name

LD78 beta (CCL3L1) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

Biologische Quelle

human

Rekombinant

expressed in E. coli

Assay

≥98% (HPLC)
≥98% (SDS-PAGE)

Form

lyophilized

Mol-Gew.

7.7 kDa

Verpackung

pkg of 20 μg

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

<0.1 EU/μg endotoxin, tested

Farbe

white to off-white

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... CCL3L1(6349)

Allgemeine Beschreibung

LD78β is a CC chemokine that is closely related to MIP-1α. It signals through the CCR5 receptor and the beta-chemokine receptor, D6. LD78β has been shown to exhibit potent activity in HIV suppression assays. Recombinant human LD78β is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Biochem./physiol. Wirkung

LD78b is a CC chemokine that is closely related to MIP-1a. It signals through the CCR5 receptor and the beta-chemokine receptor, D6. Recombinant human LD78b is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Sequenz

APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA

Physikalische Form

Lyophilized with no additives.

Rekonstituierung

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

M Nakao et al.
Molecular and cellular biology, 10(7), 3646-3658 (1990-07-01)
LD78 is a member of a newly identified superfamily of small inducible proteins involved in inflammatory responses, wound healing, and tumorigenesis. Southern blot analysis of the EcoRI-digested human genomic DNAs, using previously isolated LD78 cDNA as a probe, showed that

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