SML0482

3CAI

≥95% (HPLC)

• Synonym(e): 2-Chloro-1-(1H-indol-3-yl)ethanone, 3-Chloroacetyl-indole, Chloromethyl indol-3-yl ketone
• Empirische Formel (Hill-System): C₁₀H₈ClNO
• CAS-Nummer: 28755-03-5
• Molekulargewicht: 193.63
• MDL-Nummer: MFCD00464796
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825433
• NACRES: NA.77

Eigenschaften

• Assay: ≥95% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated; protect from light
• Farbe: yellow to brown
• Löslichkeit: DMSO: 5 mg/mL, clear
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: O=C(CCl)C1=CNC2=C1C=CC=C2
• InChI: 1S/C10H8ClNO/c11-5-10(13)8-6-12-9-4-2-1-3-7(8)9/h1-4,6,12H,5H2
• InChIKey: LLZQFAXTCYDVTR-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

3CAI is a potent and specific allosteric inhibitor of Akt1 and Akt2.

3CAI is an orally active, potent and specific allosteric inhibitor of Akt1 and Akt2 that directly binds to Ak1 and Akt2 in an ATP noncompetitive manner.

Leistungsmerkmale und Vorteile

This compound is featured on the PKB/Akt page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3