Sibiricose A5, a hydroxycinnamic acid, belongs to group of compounds known as phenylpropenoyl sucroses. This bioactive natural product is commonly available from Sibiricum sp., Polygala tenuifolia and Lilium speciosum plants. It exhibits various biological activities such as anti-inflammatory, anti-depressant, neuroprotective and anti-oxidant properties.
Anwendung
It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
Biochem./physiol. Wirkung
Sibiricose A5 has potent antioxidant activity. It is a lactate dehydrogenase inhibitor, it displays antidepressant-like actions and it is active against Alzheimer′s disease.
Leistungsmerkmale und Vorteile
High quality compound suitable for multiple research applications
Compatible with HPLC and mass spectrometry techniques
Sonstige Hinweise
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Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 33(11), 1278-1280 (2008-10-04)
To investigate the antidepressant components of Polygala tenuifolia. The chromatographic method was used to isolate and purify the chemical constituents, their structures were identified by spectral analysis, MTT method was applied to investigate their cytotoxic activities. Nine compounds were isolated
Sibiricose A5 (A5), sibiricose A6 (A6), 3,6'-disinapoyl sucrose (DSS), tenuifoliside A (TFSA) and 3,4,5-trimethoxycinnamic acid (TMCA) are the main active components of Polygala tenuifolia Willd. (Polygalaceae) (PT) that are active against Alzheimer's disease. To compare the pharmacokinetics and bioavailability of
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