SBR00088

Rilpivirine

≥95% (HPLC), powder

• Synonym(e): 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, R 278474, TMC 278
• Empirische Formel (Hill-System): C₂₂H₁₈N₆
• CAS-Nummer: 500287-72-9
• Molekulargewicht: 366.42
• MDL-Nummer: MFCD11046372
• UNSPSC-Code: 51101500

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: powder
• Farbe: white to yellow, or beige
• Wirkungsspektrum von Antibiotika: viruses
• Wirkungsweise: enzyme | inhibits
• Versandbedingung: ambient
• Lagertemp.: −20°C
• SMILES String: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N
• InChI: 1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+
• InChIKey: YIBOMRUWOWDFLG-ONEGZZNKSA-N

Beschreibung

Allgemeine Beschreibung

Rilpivirine is an antibiotic which belongs to the class of compounds known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Biochem./physiol. Wirkung

Nonnucleoside reverse transcriptase inhibitor (NNRTI); anti-retroviral

Rilpivirine inhibits the activity of the reverse transcriptase enzyme, which is essential for the replication of HIV-1. Specifically, it binds to a specific site on the enzyme and blocks its activity, thereby preventing the conversion of viral RNA into DNA, which is an essential step for the integration of viral DNA into host cells.

Rilpivirine is a next generation nonnucleoside reverse transcriptase inhibitor (NNRTI), It has been shown to be active against many HIV strains with mutations that confer resistance to the first-generation NNRTIs.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable