SAB5702738

Anti-LIN28A Antibody, clone 2S1I10, Rabbit Monoclonal

• Synonym(e): CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A
• UNSPSC-Code: 12352203
• NACRES: NA.46

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Materialien: colorless
• Klon: 2S1I10, monoclonal
• Form: liquid
• Mol-Gew.: 26 kDa
• Speziesreaktivität: human, rat, rat
• Konzentration: 0.70 mg/mL
• Methode(n): immunofluorescence: 1:50 - 1:200; western blot: 1:10000 - 1:20000
• Farbe: colorless
• Isotyp: IgG
• Immunogene Sequenz: MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKS
• UniProt-Hinterlegungsnummer: Q9H9Z2
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... LIN28A(79727)

Beschreibung

Allgemeine Beschreibung

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIN28A (Q9H9Z2).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Anwendung

WB, IF/ICC

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1