SAB5200099

Anti-HSPB2 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

• Synonym(e): Anti-Anti-HSPB2 (MKBP), Anti-DMPK-binding protein, Anti-HspB2, Anti-MGC133245, Anti-heat shock 27kDa protein 2
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous glycerol solution
• Mol-Gew.: antigen predicted mol wt 27 kDa
• Speziesreaktivität: rat, human, mouse
• Konzentration: 1 mg/mL
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_001532.1
• UniProt-Hinterlegungsnummer: Q16082
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... HSPB2(3316)

Beschreibung

Allgemeine Beschreibung

Heat shock protein family B, member 2 (HSPB2) is also called as myotonic dystrophy kinase binding protein (MKBP). It is expressed in the skeletal muscles and heart. Studies have also shown that HSPB2 is overexpressed in lung fibrosis. The gene encoding it is localized on human chromosome 11q22-q23. The gene ID of the protein is 3316.

Spezifität

Detects ~27 kDa.

Immunogen

Synthetic peptide

Biochem./physiol. Wirkung

Heat shock protein family B, member 2 (HSPB2) binds to ubiquitin and hydrogen peroxide-inducible clone 5, an adaptor protein. This association is important for the ubiquitination and degradation of NADPH oxidase 4 (Nox4). It is also crucial for the degradation of other proteins. HSPB2 interacts with myotonic dystrophy protein kinase (DMPK) and activates it.

Leistungsmerkmale und Vorteile

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Physikalische Form

PBS, 50% glycerol, and 0.02% sodium azide

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable