SAB4300241

Anti-phospho-MAPKAPK2 (pThr³³⁴) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-MK2 antibody produced in rabbit, Anti-mitogen-activated protein kinase-activated protein kinase 2 antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~49 kDa
• Speziesreaktivität: human, rat, mouse
• Konzentration: 1 mg/mL
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (P-Q-TP-P-L)
• NCBI-Hinterlegungsnummer: NP_004750.1
• UniProt-Hinterlegungsnummer: P49137
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pThr334)
• Angaben zum Gen: human ... MAPKAPK2(9261)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of threonine 334 (P-Q-T(p)-P-L), according to the protein MAPKAPK2.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

MAPKAPK-2 encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable