SAB4300231

Anti-phospho-GAB1 (pTyr⁶²⁷) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-GRB2-associated binding protein 1 antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~110 kDa
• Speziesreaktivität: mouse, human
• Konzentration: 1 mg/mL
• Methode(n): indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (V-E-YP-L-D)
• NCBI-Hinterlegungsnummer: NP_002030.2
• UniProt-Hinterlegungsnummer: Q13480
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr627)
• Angaben zum Gen: human ... GAB1(2549)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y(p)-L-D), according to the protein GAB1.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable