SAB4300113

Anti-phospho-FOXO4 (pSer¹⁹⁷) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-AFX antibody produced in rabbit, Anti-AFX1 antibody produced in rabbit, Anti-MGC120490 antibody produced in rabbit, Anti-MLLT7 antibody produced in rabbit, Anti-forkhead box O4 antibody produced in rabbit
• MDL-Nummer: MFCD03791410
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~65 kDa
• Speziesreaktivität: human, rat, mouse
• Konzentration: 1 mg/mL
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (A-A-SP-M-D)
• NCBI-Hinterlegungsnummer: NP_001164402.1
• UniProt-Hinterlegungsnummer: P98177
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer197)
• Angaben zum Gen: human ... FOXO4(4303)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of serine 197 (A-A-S(p)-M-D), according to the protein FOXO4.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable