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Merck

SAB3701436

Sigma-Aldrich

Monoclonal Anti-Hsc70 (Hsp73) antibody produced in mouse

clone N27F3-4, purified immunoglobulin

Synonym(e):

Anti-HSC54 antibody, Anti-HSC71 antibody, Anti-Heat shock protein 8 antibody, Anti-Heat-shock70-KD protein 10, Anti-MHV-A59

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.43

Biologische Quelle

mouse

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

N27F3-4, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

canine, bovine, salmon, beluga, rat, Caenorhabditis elegans, human, carp, Drosophila, mouse, chicken

Methode(n)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

Isotyp

IgG1

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... HSPA1A(3303)

Spezifität

This Protein G purified monoclonal antibody reacts with human Hsc70 (Hsp73) protein.   A BLAST analysis was used to suggest cross-reactivity with Hsc70 from human, bovine, mouse, rat, C.elegans, beluga, dog, chicken, Drosophila, carp, salmon, trout, guinea pig, hamster, monkey, pig, cucumber, pea, rabbit, sheep and Xenopus sources based on 100% homology with the immunizing sequence.  This antibody recognizes both the inducible hsp and the constitutively expressed hsc as 72 kDa and 73 kDa proteins, respectively.  Cross-reactivity with Hsp70 from other sources has not been determined.

Immunogen

Synthetic peptide corresponding to a region of human Hsc70 (Hsp73) protein.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.1% (w/v) Sodium Azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Hashim Ali et al.
Nature communications, 10(1), 926-926 (2019-02-26)
Productive HIV-1 replication requires viral integrase (IN), which catalyzes integration of the viral genome into the host cell DNA. IN, however, is short lived and is rapidly degraded by the host ubiquitin-proteasome system. To identify the cellular factors responsible for

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