Direkt zum Inhalt
Merck

SAB3500141

Sigma-Aldrich

Anti-TRESK antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-KCNK18, Anti-Potassium channel subfamily K member 18, Anti-TRESK2, Anti-TRIK

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

human, rat, mouse

Methode(n)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... KCNK18(338567)

Allgemeine Beschreibung

Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK is part of the potassium channel family. It is expressed in trigeminal and dorsal root ganglions. The protein is activated by calcium signals. The TRESK gene is localized on human chromosome 10q25.3.

Immunogen

TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK.

Biochem./physiol. Wirkung

Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK contributes to background K+ currents in sensory neurons. Mutations in the gene encoding it have been associated with familial migraine with aura.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP3500141.

Physikalische Form

Supplied in PBS with 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Involvement of gap junction channels in the pathophysiology of migraine with aura
Denis Sarrouilhe
Frontiers in Physiology (2014)
KCNK18 (TRESK) genetic variants in Italian patients with migraine.
Rainero I
Headache (2014)
Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel.
Bruner JK
European Journal of Pharmacology (2014)
TRESK: the lone ranger of two-pore domain potassium channels.
Enyedi P
Molecular and Cellular Endocrinology (2012)

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