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SAB2501370

Sigma-Aldrich

Anti-SNAI1 (N-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-SLUGH2, Anti-SNA, Anti-SNAH, Anti-dJ710H13.1, Snail homolog 1 (Drosophila)

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

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100 μG
CHF 437.00

CHF 437.00


Voraussichtliches Versanddatum29. April 2025



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100 μG
CHF 437.00

About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

CHF 437.00


Voraussichtliches Versanddatum29. April 2025


Biologische Quelle

goat

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

rat, human

Methode(n)

indirect ELISA: suitable

UniProt-Hinterlegungsnummer

Anwendung(en)

research pathology

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... SNAI1(6615)

Allgemeine Beschreibung

Snail family transcriptional repressor 1 (SNAIL) is a transcription factor and the gene encoding it is localized on human chromosome 20q13.13.

Immunogen

Peptide with sequence RKPSDPNRKPNY-C, from the N-terminal region of the protein sequence according to NP_005976.2

Biochem./physiol. Wirkung

Snail family transcriptional repressor 1 (SNAIL) acts as a repressor of genes associated with the epithelial phenotype like E-cadherin and increases the expression of genes linked with the mesenchymal phenotype. It has a role in epithelial-mesenchymal transition. The protein aids in G1 transition (early to late) in the cell cycle. SNAIL also modulates cell-matrix adhesion.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

TP53 Mutation, Epithelial-Mesenchymal Transition, and StemlikeFeatures in Breast Cancer Subtypes
Danila Coradini
Journal of Biomedicine and Biotechnology (2012)
CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells.
Haraguchi M
PLoS ONE (2015)
SNAIL transcription factor increases the motility and invasive capacity of prostate cancer cells.
Osorio LA
Molecular Medicine Reports (2016)
Jessica Catapano et al.
Cellular & molecular biology letters, 27(1), 100-100 (2022-11-20)
Metformin is an inhibitor of oxidative phosphorylation that displays an array of anticancer activities. The interference of metformin with the activity of multi-drug resistance systems in cancer cells has been reported. However, the consequences of the acquired chemoresistance for the
Paweł Kochanowski et al.
International journal of molecular sciences, 22(8) (2021-05-01)
Glioblastoma multiforme (GBM) recurrences after temozolomide (TMZ) treatment result from the expansion of drug-resistant and potentially invasive GBM cells. This process is facilitated by O6-Methylguanine-DNA Methyltransferase (MGMT), which counteracts alkylating TMZ activity. We traced the expansion of invasive cell lineages

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