SAB1305503

MONOCLONAL ANTI-CD25 antibody produced in mouse

clone 7G7B6, crude ascites, buffered aqueous solution

• Synonym(e): CD_antigen=CD25, IL2RA, Interleukin-2 receptor subunit alpha, TAC antigen, p55
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Antikörperform: crude ascites
• Antikörper-Produkttyp: primary antibodies
• Klon: 7G7B6, monoclonal
• Form: buffered aqueous solution
• Mol-Gew.: 30819 Da
• Speziesreaktivität: human
• Methode(n): western blot: 1:100-~1:800
• Isotyp: IgG2a
• NCBI-Hinterlegungsnummer: NP_000408.1
• UniProt-Hinterlegungsnummer: P01589
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... IL2RA(3559)

Beschreibung

Allgemeine Beschreibung

The CD25 gene, also referred to as IL2RA (interleukin 2 receptor subunit α), is mapped to human chromosome 10p15. The gene spans a length of 48 kb with eight exons.

Biochem./physiol. Wirkung

The interleukin 2 receptor subunit α (IL2RA) gene encodes the α-chain of the IL-2 receptor complex. This receptor complex, made up of α, β, and a common γ chain, binds to its ligand, IL-2, which is a crucial growth factor for T- and B-cells. This ligand-receptor complex plays an important role in the regulation of immune responses. Variation in the chromosomal region containing this gene is associated with type 1 diabetes. This region is also linked to autoimmune thyroid disease indicating its role in autoimmunity. IL2RA has been found to confer a risk for multiple sclerosis.

Physikalische Form

Supplied in PBS with 0.09% (W/V) sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable