SAB1300136

Monoclonal Anti-LIN28A antibody produced in mouse

IgG fraction of antiserum, buffered aqueous solution

• Synonym(e): Anti-CSDD1, Anti-LIN28, Anti-LIN28A, Anti-Lin-28 homolog A, Anti-Zinc finger CCHC domain-containing protein 1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Konjugat: unconjugated
• Antikörperform: IgG fraction of antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: 55CT58.12.1, monoclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000; western blot: 1:100-1:500
• Isotyp: IgG1
• NCBI-Hinterlegungsnummer: NP_078950
• UniProt-Hinterlegungsnummer: Q9H9Z2
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... LIN28A(79727)

Beschreibung

Allgemeine Beschreibung

LIN28A acts as a ′translational enhancer′, driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression. LIN28A recombinant protein is used to produce this monoclonal antibody.

Immunogen

LIN28A (NP_078950, Recombinant Protein)
LIN28A recombinant protein is used to produce this monoclonal antibody.

Physikalische Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable