Direkt zum Inhalt
Merck

S9317

Sigma-Aldrich

PAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt

≥97% (HPLC)

Synonym(e):

PAR2-AP, SLIGRL−NH2, Ser-Leu-Ile-Gly-Arg-Leu-amide trifluoroacetate salt

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Größe auswählen

1 MG
CHF 115.00

CHF 115.00


Check Cart for Availability

Bulk-Bestellung anfordern

Größe auswählen

Ansicht ändern
1 MG
CHF 115.00

About This Item

Empirische Formel (Hill-System):
C29H56O7N10 · C2HF3O2
Molekulargewicht:
770.84
MDL-Nummer:
UNSPSC-Code:
51111800
PubChem Substanz-ID:
NACRES:
NA.32

CHF 115.00


Check Cart for Availability

Bulk-Bestellung anfordern

Qualitätsniveau

Assay

≥97% (HPLC)

Form

solid

Lagertemp.

−20°C

SMILES String

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O

InChI

1S/C29H56N10O7/c1-7-17(6)23(39-27(45)21(12-16(4)5)38-25(43)18(30)14-40)28(46)35-13-22(41)36-19(9-8-10-34-29(32)33)26(44)37-20(24(31)42)11-15(2)3/h15-21,23,40H,7-14,30H2,1-6H3,(H2,31,42)(H,35,46)(H,36,41)(H,37,44)(H,38,43)(H,39,45)(H4,32,33,34)/t17-,18-,19-,20-,21-,23-/m0/s1

InChIKey

SGPMJRPYYIJZPC-JYAZKYGWSA-N

Amino Acid Sequence

Ser-Leu-Ile-Gly-Arg-Leu-NH2

Anwendung

PAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt has been used as a proteinase-activated receptor 2 (PAR-2) agonist to induce the expression of Hh and Hippo genes in Hek293A cells.[1]

Biochem./physiol. Wirkung

Selective proteinase-activated receptor 2 (PAR2) peptide agonist.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

The Yes-associated protein controls the cell density regulation of Hedgehog signaling
M. Tariki
Oncogenesis (2014)
Hyun Su Ha et al.
Archives of pharmacal research, 40(12), 1443-1454 (2017-11-04)
Protease-activated receptors (PARs) are a family of G protein-coupled receptors with a unique activation mechanism involving proteolytic cleavage of the extracellular N-terminal domain of the receptor. PAR2 has a contractile effect on esophageal smooth muscle. We investigate the signaling pathways
Chihiro Hirai et al.
Reproductive sciences (Thousand Oaks, Calif.), 23(11), 1542-1550 (2016-05-04)
The production of soluble fms-like tyrosine kinase 1 (sFLT1) by exogenous chymotrypsin in trophoblast cells through protease-activated receptor (PAR) 2 was investigated to identify the role of a chymotrypsin-like serine protease in preeclampsia (PE) pathogenesis. We evaluated the expression of
Tomoki Fukuyama et al.
BMC pharmacology & toxicology, 19(1), 37-37 (2018-07-05)
Topical administration of PR022, 0.05% hypochlorous acid (HOCl) in gel has been demonstrated to be beneficial in a chronic murine atopic dermatitis model. In a follow up study we tested a higher concentration (0.1%) of PR022 HOCl gel in comparison
Chengcheng Huang et al.
Frontiers in molecular neuroscience, 10, 205-205 (2017-07-14)
Itch, a sensation eliciting a desire to scratch, is distinct from but not completely independent of pain. Inspiring achievements have been made in the characterization of itch-related receptors and neurotransmitters, but the molecular mechanisms controlling the development of pruriceptors remain

Questions

Reviews

No rating value

Active Filters

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.