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Merck

S8508

Sigma-Aldrich

[Tyr11]-Somatostatin

≥90% (HPLC)

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About This Item

Empirische Formel (Hill-System):
C76H104N18O20S2
CAS-Nummer:
Molekulargewicht:
1653.88
MDL-Nummer:
UNSPSC-Code:
12352200

Assay

≥90% (HPLC)

Lagertemp.

−20°C

SMILES String

CC(N)C(=O)NCC(=O)NC1CSSCC(NC(=O)C(CO)NC(=O)C(NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(Cc3c[nH]c4ccccc34)NC(=O)C(Cc5ccccc5)NC(=O)C(Cc6ccccc6)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC1=O)C(C)O)C(C)O)C(O)=O

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

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S J Sullivan et al.
Endocrinology, 122(3), 1137-1145 (1988-03-01)
Previous studies with heterogeneous populations of pancreatic cells have provided evidence for the presence of somatostatin (SRIF) receptors in cytosol and secretion vesicles, as well as the plasma membrane. To examine the distribution of SRIF receptors between soluble and membrane
B Colás et al.
Journal of receptor research, 7(5), 653-666 (1987-01-01)
Specific binding sites for somatostatin have been detected in cytosolic fraction of bovine cystic duct mucosa. At 37 degrees C, the interaction of 125I-Tyr11-somatostatin with cytosolic fraction was rapid, reversible, specific and saturable. At equilibrium, the binding of tracer was
A Schonbrunn et al.
Endocrinology, 132(1), 146-154 (1993-01-01)
The neuropeptide somatostatin (SRIF) triggers its biological effects by binding to high affinity membrane receptors. To develop a ligand useful for receptor affinity purification and localization, we have examined the ability of a novel monobiotinylated SRIF derivative to bind to
R Tatoud et al.
Molecular and cellular endocrinology, 113(2), 195-204 (1995-09-22)
We investigated somatostatin receptors (SSTRs) in surgical specimens of prostate cancer and benign prostate hyperplasia (BPH), a normal immortalized epithelial cell line (PNT1), epithelial cancer cell lines, and stromal cells in short-term culture derived from normal and BPH biopsies. Cross-linking
M N Rodríguez-Sánchez et al.
Peptides, 12(5), 951-956 (1991-09-01)
The effects of cocaine administration to pregnant and/or nursing rats on somatostatin (SS) concentration and receptors in offspring brains at birth and 15 days of age were studied. SS was measured by radioimmunoassay and SS receptors by radio receptor assay

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