S8201

SR-3576

≥98% (HPLC)

• Synonym(e): 3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide, 3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide
• Empirische Formel (Hill-System): C₂₇H₂₇N₅O₅
• CAS-Nummer: 1164153-22-3
• Molekulargewicht: 501.53
• MDL-Nummer: MFCD18632556
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329824599
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: light brown to brown
• Löslichkeit: DMSO: ≥20 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: COc1cc(NC(=O)c2cccc(c2)-n3cc(NC(=O)Nc4cccc(C)c4)cn3)cc(OC)c1OC
• InChI: 1S/C27H27N5O5/c1-17-7-5-9-19(11-17)30-27(34)31-21-15-28-32(16-21)22-10-6-8-18(12-22)26(33)29-20-13-23(35-2)25(37-4)24(14-20)36-3/h5-16H,1-4H3,(H,29,33)(H2,30,31,34)
• InChIKey: MTFAYLZZDJGFGV-UHFFFAOYSA-N

Beschreibung

Anwendung

SR-3576 may be used in JNK3-mediated cell signaling studies.

Biochem./physiol. Wirkung

SR-3576 is a cell-permeable, potent and selective JNK3 (c-Jun N-terminal kinase 3) inhibitor.

SR-3576 is a small molecule inhibitor belonging to aminopyrazole class that selectively inhibits JNK3 with >2800 fold selectively over p38.¹

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable