S0648

Secretin, porcine

~25 units/mg solid, from Porcine intestinal mucosa

• Empirische Formel (Hill-System): C₁₃₀H₂₂₀N₄₄O₄₁
• CAS-Nummer: 17034-35-4
• Molekulargewicht: 3055.41
• Beilstein: 741850
• EG-Nummer: 241-105-3
• MDL-Nummer: MFCD00133810
• UNSPSC-Code: 12352200

Eigenschaften

• Biologische Quelle: Porcine intestinal mucosa
• Spezifische Aktivität: ~25 units/mg solid
• Verpackung: vial of ~100 Crick-Harper-Raper units
• Löslichkeit: H₂O: soluble; saline: soluble
• UniProt-Hinterlegungsnummer: P63298
• Lagertemp.: 2-8°C
• SMILES String: [H]N[C@@H](CC(O)=O)C(O)=O.[H]N[C@@H](CC(O)=O)C(O)=O.[H]N[C@@H](CC(O)=O)C(O)=O.[H]N[C@@H](CC(O)=O)C(O)=O.[H]N[C@@H](CC(O)=O)C(O)=O.[H]N[C@@H](CC(O)=O)C(O)=O.[H]N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C(C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O
• InChI: 1S/C130H220N44O41.6C4H7NO4/c1-59(2)41-79(119(208)173-99(65(13)14)102(134)191)152-94(183)52-148-105(194)76(31-34-92(132)181)157-114(203)82(44-62(7)8)164-116(205)83(45-63(9)10)162-108(197)73(28-22-38-145-128(137)138)154-111(200)77(32-35-93(133)182)158-115(204)81(43-61(5)6)160-107(196)72(27-21-37-144-127(135)136)153-103(192)66(15)151-121(210)88(54-175)169-118(207)87(50-98(189)190)166-110(199)74(29-23-39-146-129(139)140)155-113(202)80(42-60(3)4)161-109(198)75(30-24-40-147-130(141)142)156-122(211)90(56-177)170-117(206)84(46-64(11)12)163-112(201)78(33-36-96(185)186)159-123(212)91(57-178)171-126(215)101(68(17)180)174-120(209)85(47-69-25-19-18-20-26-69)167-125(214)100(67(16)179)172-95(184)53-149-106(195)86(49-97(187)188)165-124(213)89(55-176)168-104(193)71(131)48-70-51-143-58-150-70;6*5-2(4(8)9)1-3(6)7/h18-20,25-26,51,58-68,71-91,99-101,175-180H,21-24,27-50,52-57,131H2,1-17H3,(H2,132,181)(H2,133,182)(H2,134,191)(H,143,150)(H,148,194)(H,149,195)(H,151,210)(H,152,183)(H,153,192)(H,154,200)(H,155,202)(H,156,211)(H,157,203)(H,158,204)(H,159,212)(H,160,196)(H,161,198)(H,162,197)(H,163,201)(H,164,205)(H,165,213)(H,166,199)(H,167,214)(H,168,193)(H,169,207)(H,170,206)(H,171,215)(H,172,184)(H,173,208)(H,174,209)(H,185,186)(H,187,188)(H,189,190)(H4,135,136,144)(H4,137,138,145)(H4,139,140,146)(H4,141,142,147);6*2H,1,5H2,(H,6,7)(H,8,9)/t66-,67+,68+,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,99-,100-,101-;6*2-/m0000000/s1
• InChIKey: KYSAMAXXLYMNME-INRVZKLKSA-N
• Angaben zum Gen: pig ... SCT(397464)

Beschreibung

Amino Acid Sequence

His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH₂

Biochem./physiol. Wirkung

Stimulates secretion of carbonate-rich pancreatic fluid; relaxes smooth muscle

Angaben zur Herstellung

teilweise gereinigt

Hinweis zur Analyse

Activity determined by RIA using pure synthetic porcine secretin as standard.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)