R6525

Anti-phospho-Rsk1 (p90^rsk) (pSer³⁸¹) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

• Synonym(e): Anti-phospho-Rsk 1 (pSer³⁸¹)
• MDL-Nummer: MFCD02097169
• UNSPSC-Code: 12352203
• NACRES: NA.44

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous glycerol solution
• Speziesreaktivität: mouse, rat, human
• Methode(n): immunocytochemistry: 1:2,000; immunoprecipitation (IP): 1:200; western blot (chemiluminescent): 1:1,000 using TPA-treated 293 cell extract
• UniProt-Hinterlegungsnummer: Q15418
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... RPS6KA1(6195) ; mouse ... Rps6ka1(20111) ; rat ... Rps6ka1(81771)

Beschreibung

Allgemeine Beschreibung

Rsk1 is a ubiquitously expressed, mitogen-activated protein that belongs to the serine/threonine protein kinase family. It has a pivotal role in facilitating MEK-MAP kinase cell survival signaling and supressing pro-apoptotic function of BAD by its phosphorylation. Anti-phospho-Rsk1 (p90rsk) (pSer381) antibody can be used to detect Rsk1 when phosphorylated at phosphoserine 381. It can also be used in immunoprecipitation (diluted 1:200). Rabbit anti-phospho-Rsk1 (p90rsk) (pSer381) antibody reacts specifically with phosphorylated Rsk1 and not with nonphosphorylated Rsk1. The product has also specificity for Rsk1 of rat, mouse and human.

Immunogen

Synthetic phospho-Ser381 peptide corresponding to residues around Ser381 of human (p90rsk) conjugated to KLH.

Anwendung

Anti-phospho-Rsk1 (p90rsk) (pSer381) antibody can be used in western blotting (diluted 1:1000) using TPA-treated 293 cell extract. It can also be used in immunocytochemistry (diluted 1:2000).

Physikalische Form

Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable