PLA0012

Rabbit anti-Phospho SMC1 (S957) Antibody, Affinity Purified

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• Synonym(e): CDLS2, DXS423E, KIAA0178, SB1.8, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1, SMC1 (structural maintenance of chromosomes 1, SMC1 structural maintenance of chromosomes 1-like 1 (yeast), SMC1L1, SMC1alpha, Smcb, segregation of mitotic chromosomes 1, yeast)-like 1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Speziesreaktivität: human
• Methode(n): immunoprecipitation (IP): 2- 6 μg/mg; western blot: 1:200-1:2,000
• Hinterlegungsnummer: NP_006297.2
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Angaben zum Gen: human ... SMC1A(8243)

Beschreibung

Immunogen

Immunogen for PLA0012 was a phosphorylated synthetic peptide, which represented a portion of human Structural Maintenance of Chromosomes 1 (GeneID 8243) around serine 957 according to the numbering given in entry NP_006297.2.

Physikalische Form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Sonstige Hinweise

Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable