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Merck

P8109

Sigma-Aldrich

Anti-Serine/Threonine Protein Phosphatase 2 A/A antibody produced in rabbit

~1 mg/mL, IgG fraction of antiserum, buffered aqueous solution

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.44

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

IgG fraction of antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 65 kDa

Speziesreaktivität

bovine, human, rat, mouse

Konzentration

~1 mg/mL

Methode(n)

immunocytochemistry: 10-15 μg/mL
microarray: suitable
western blot: 5-10 μg/mL using total rat brain homogenate

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PPP2CA(5515)
mouse ... Ppp2ca(19052)
rat ... Ppp2ca(24672)

Allgemeine Beschreibung

Protein Phosphatase 2A (PP2A) is a protein that belongs to serine/threonine-specific protein phosphatases family. It has a pivotal role in several cellular processes like DNA replication, transcription, RNA splicing, translation, cellular metabolism, cell-cycle progression, morphogenesis, development and transformation. Anti-serine/threonine protein phosphatase 2 A/A antibody can be used for detecting protein phosphatase 2A/A isoforms by using immunoprecipitation. It can also be used in immunocytochemistry. Rabbit anti-serine/threonine protein phosphatase 2 A/A antibody reacts specifically with protein phosphatase 2A/A isoforms (65kD) from mouse, bovine, rat and human.

Immunogen

synthetic peptide corresponding to the N-terminus (amino acids 7-19) of the protein phosphatase 2A structural subunit.

Anwendung

Anti-serine/threonine protein phosphatase 2 A/A antibody can be used in western blotting using total rat brain homogenate. It can also be used in microarray.

Physikalische Form

Solution in phosphate buffered saline containing 0.08% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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10 - Combustible liquids


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R E Mayer-Jaekel et al.
Trends in cell biology, 4(8), 287-291 (1994-08-01)
Protein phosphorylation is probably the major regulatory mechanism employed by eukaryotic cells. Much work has been devoted to the role of protein kinases and their modulation by hormones, growth factors and neurotransmitters. It is now appreciated that protein phosphatases are
Serine/threonine protein phosphatases.
S Wera et al.
The Biochemical journal, 311 ( Pt 1), 17-29 (1995-10-01)
W Rozek et al.
Polish journal of veterinary sciences, 16(4), 663-669 (2013-01-01)
Changes in the level of cellular proteins in cells inoculated with equine influenza virus H7N7 and H3N8 were studied with microarray technique. H3N8 induced pro-apoptotic proteins while H7N7 induced both pro- as well as anti-apoptotic factors. The higher level of

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