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Ursprungszeugnis (CoO)/Analysenzertifikate (CoA)

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P7053

N-Phenylacetyl-Gly-Lys

Name: N-Phenylacetyl-Gly-Lys
Brand: SIGMA

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About This Item

Empirische Formel (Hill-System):

C₁₆H₂₃N₃O₄

CAS-Nummer:

113969-25-8

Molekulargewicht:

321.37

MDL-Nummer:

MFCD00135803

UNSPSC-Code:

12352200

PubChem Substanz-ID:

24898815

Lagertemp.

−20°C

SMILES String

NCCCCC(NC(=O)CNC(=O)Cc1ccccc1)C(O)=O

InChI

1S/C16H23N3O4/c17-9-5-4-8-13(16(22)23)19-15(21)11-18-14(20)10-12-6-2-1-3-7-12/h1-3,6-7,13H,4-5,8-11,17H2,(H,18,20)(H,19,21)(H,22,23)

InChIKey

VPCYMTNCRVUYFU-UHFFFAOYSA-N

Sonstige Hinweise

Peptide that is 50 times sweeter than sucrose

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Elucidation of a novel polypeptide cross-link involving 3-hydroxykynurenine.

J A Aquilina et al.

Biochemistry, 38(35), 11455-11464 (1999-09-02)

3-Hydroxykynurenine, a metabolite of tryptophan, is a powerful antioxidant and neurotoxin. The neurotoxicity results from the oxidation of 3-hydroxykynurenine, and hydroxyl radicals, formed via H(2)O(2), may also be implicated [Okuda, S., Nishiyama, N., Saito, H. , and Katsuki, H. (1996)

Polypeptide modification and cross-linking by oxidized 3-hydroxykynurenine.

J A Aquilina et al.

Biochemistry, 39(51), 16176-16184 (2000-12-22)

3-Hydroxykynurenine (3OHKyn) is present in the mammalian lens as a UV filter and is formed from kynurenine in the tryptophan metabolic pathway. 3OHKyn is a readily autoxidized o-aminophenol which binds to proteins in vitro. The lens, particularly its central region

Nosho, Y. and Ohfuji, T.

Chemical and Engineering News, 68(2), 25-25 (1990)

3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody.

Magdalena M Staniszewska et al.

The Journal of biological chemistry, 280(23), 22154-22164 (2005-04-09)

Tryptophan can be oxidized in the eye lens by both enzymatic and non-enzymatic mechanisms. Oxidation products, such as kynurenines, react with proteins to form yellow-brown pigments and cause covalent cross-linking. We generated a monoclonal antibody against 3-hydroxykynurenine (3OHKYN)-modified keyhole limpet

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