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O3011
Oxiracetam
Synonym(e):
4-Hydroxy-2-oxopyrrolidine-N-acetamide
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About This Item
Empirische Formel (Hill-System):
C6H10N2O3
CAS-Nummer:
Molekulargewicht:
158.16
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
Empfohlene Produkte
Lagertemp.
2-8°C
SMILES String
NC(=O)CN1CC(O)CC1=O
InChI
1S/C6H10N2O3/c7-5(10)3-8-2-4(9)1-6(8)11/h4,9H,1-3H2,(H2,7,10)
InChIKey
IHLAQQPQKRMGSS-UHFFFAOYSA-N
Biochem./physiol. Wirkung
Nootropic agent, improves learning and memory, and prevents impairment of cognitive functions. Its mechanism of action in not yet known, but it is suggested to modulate glutamatergic and cholinergic neurotransmission. Protein kinase C may be involved.
Nootropic agent, improves learning and memory.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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Z Hlinák et al.
European journal of pharmacology, 314(1-2), 1-7 (1996-10-24)
In the present study, the elevated plus-maze was used to evaluate memory in female mice. In Experiment 1, the mice retested on day 1, 4 or 7 after the initial session escaped from the open arm into the enclosed arm
L de Angelis et al.
Neurobiology of learning and memory, 64(2), 119-124 (1995-09-01)
The effects of a nootropic drug, oxiracetam (50-100-200 mg/kg ip), and a potent antioxidant agent, ascorbic acid (62.5-125-250 mg/kg ip), administered alone or in combination, were investigated on scopolamine-induced amnesia in a mouse habituation test. The light-dark aversion test was
M Pinza et al.
Journal of medicinal chemistry, 36(26), 4214-4220 (1993-12-24)
A series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones were synthesized. These bicylic derivatives contain both the 2-pyrrolidinone and 4-imidazolidinone nuclei, already recognized as important for cognition enhancing activity. In addition, these structures maintain the backbone of piracetam and oxiracetam with the acetamide side chain
I N Krylov et al.
Biulleten' eksperimental'noi biologii i meditsiny, 115(3), 260-262 (1993-03-01)
Acute exposure of rats to microwaves (12.6 chr, 2375 MHz, power density 1 mW/cm2) induced the retrograde amnesia. It was show the role of opioidergic, benzodiazepine, GABAergic and cholinergic components in the amnesic effects of microwaves. Piracetam (100 mg/kg, i.
Xiang-Xi Yi et al.
Pharmaceutical biology, 58(1), 1211-1220 (2020-12-08)
Fruit of Avicennia marina (Forsk.) Vierh. (Acanthaceae) is used as a Chinese herb. Studies have found that it contains marinoid J, a novel phenylethanoid glycoside (PG) compound, but its neuroprotective functions are largely unknown. This study evaluated the effects of
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