M3778

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

≥97% (GC), MAO-A inhibitor, powder

• Synonym(e): Clorgyline
• Empirische Formel (Hill-System): C₁₃H₁₅Cl₂NO · HCl
• CAS-Nummer: 17780-75-5
• Molekulargewicht: 308.63
• NACRES: NA.77
• PubChem Substance ID: 24278179
• UNSPSC Code: 12352116
• EC Number: 241-760-5
• MDL number: MFCD00052012
• Assay: ≥97% (GC)
• Form: powder

Eigenschaften

• Produktname: N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride, ≥97% (GC)
• Quality Segment: 100
• assay: ≥97% (GC)
• form: powder
• solubility: DMSO: 10 mg/mL, clear, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: Cl.CN(CCCOc1ccc(Cl)cc1Cl)CC#C
• InChI: 1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H
• InChI key: BBAZDLONIUABKI-UHFFFAOYSA-N
• Gene Information: human ... MAOA(4128) ; rat ... Maoa(29253), Maob(25750)

Beschreibung

Application

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride has been used as a monoamine oxidase A (MAO-A) inhibitor:

• in MAO-A biochemical assay[1]
• to study its effects on the transit of serotonin (5-HT) in the human placenta explants[2]
• to study its effects on human prostate cancer cells[3]

Biochem/physiol Actions

MAO-A inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H312 + H332
• pcodes: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves