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L8250

Sigma-Aldrich

DL-Leucinamide hydrochloride

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About This Item

Empirische Formel (Hill-System):
C6H14N2O · HCl
CAS-Nummer:
10466-60-1
Molekulargewicht:
166.65
MDL-Nummer:
MFCD00070244
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24896497

Assay

≥98% (TLC)

Form

powder

Farbe

white

SMILES String

Cl.CC(C)CC(N)C(N)=O

InChI

1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H

InChIKey

VSPSRRBIXFUMOU-UHFFFAOYSA-N

Biochem./physiol. Wirkung

DL-Leucinamide hydrochloride is a racemic mixture of D- and L- enantiomers of leucinamide. Leucinamide is an amide derivative of leucine found at the C-terminal of various peptides such as the PAR-2 activating peptide SLIGRL-NH(2).

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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Hidenobu Komeda et al.
Applied microbiology and biotechnology, 70(4), 412-421 (2005-07-08)
Brevundimonas diminuta TPU 5720 produces an amidase acting L-stereoselectively on phenylalaninamide. The enzyme (LaaA(Bd)) was purified to electrophoretic homogeneity by ammonium sulfate fractionation and four steps of column chromatography. The final preparation gave a single band on SDS-PAGE with a
Yasuhiko Hashida et al.
Journal of biochemistry, 141(6), 879-888 (2007-04-05)
Thermolysin activity in the hydrolysis of N-[3-(2-furyl)acryloyl]-glycyl-l-leucine amide (FAGLA) and FA-l-leucyl-l-alanine amide (FALAA) was examined at various Co(2+) and Ca(2+) concentrations. It decreased to 28% with increasing [Co(2+)] up to 18 mM. The Co(2+)-dependent inactivation was in part suppressed by
R Pacheco et al.
Analytical biochemistry, 346(1), 49-58 (2005-09-28)
This study demonstrates the use of Fourier transform infrared (FTIR) spectroscopy for monitoring both synthesis and hydrolysis reactions catalyzed by a recombinant amidase (EC 3.5.1.4) from Pseudomonas aeruginosa. The kinetics of hydrolysis of acetamide, propionamide, butyramide, acrylamide, benzamide, phenylalaninamide, alaninamide
Deepak K Bhatt et al.
Headache, 50(6), 1017-1030 (2010-05-22)
The goal of this study was to determine the vascular effects of protease-activated receptor-2 (PAR-2) activation in the rat cranial vasculature. The role of PAR-2 in pain and inflammatory conditions has been established but the information available on its effects
[Marked dissociation of leucine aminopeptidase activities by the use of 2 different substrates--application of the methods to lymphatic diseases].
Y Hirasawa et al.
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 45(5), 907-912 (1982-09-01)
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