I4909
Ifosfamid
≥98%
Synonym(e):
Ifex, N,3-Bis-(2-chlorethyl)-tetrahydro-2H-1,3,2-oxazaphosphorin-2-amin-2-oxid
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Alle Fotos(3)
About This Item
Empirische Formel (Hill-System):
C7H15Cl2N2O2P
CAS-Nummer:
Molekulargewicht:
261.09
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.25
Empfohlene Produkte
Assay
≥98%
Versandbedingung
wet ice
Lagertemp.
2-8°C
SMILES String
ClCCNP1(=O)OCCCN1CCCl
InChI
1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)
InChIKey
HOMGKSMUEGBAAB-UHFFFAOYSA-N
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Verwandte Kategorien
Anwendung
- Ewing sarcoma of the pancreas: a pediatric case report and narrative literature review: This study explores the effectiveness of Ifosfamide in the treatment of rare pediatric Ewing sarcoma of the pancreas, providing valuable insights into the chemotherapeutic management of rare cancers (Liu et al., 2024).
- Prognostic value of hemogram parameters in osteosarcoma: The French OS2006 experience: Highlights the role of Ifosfamide in osteosarcoma treatment as part of a clinical trial, evaluating its impact on survival rates and treatment outcomes (Bastard et al., 2024).
- Case report: Characteristics and nature of primary cardiac synovial sarcoma: Discusses the utilization of Ifosfamide in managing primary cardiac synovial sarcoma, with an emphasis on its pharmacodynamics and therapeutic efficacy (Kawasaki et al., 2024).
- Dedifferentiated liposarcoma of the spermatic cord: Examines Ifosfamide′s mechanism of action in treating dedifferentiated liposarcoma, contributing to the broader understanding of its application in sarcoma therapy (Panther et al., 2024).
- A Rare Case of Extranodal Natural Killer/T-cell Lymphoma, Nasal Type Associated With Hemophagocytic Lymphohistiocytosis in a Patient With Recurrent Sinusitis: This article details the clinical use of Ifosfamide in treating aggressive lymphoma, underscoring its role in complex cases where standard treatments may not suffice (Christensen et al., 2024).
Biochem./physiol. Wirkung
Ifosfamid ist eine Stickstoff-Senfgas-Verbindung und ein strukturelles Isomer von Cyclophosphamid. Ifosfamid ist ein Prodrug und muss durch das Cytochrom P450 zur biologisch aktiven Komponente transformiert werden. Es wird als antineoplastischer Wirkstoff in der Chemotherapie verwendet, doch die Wahrscheinlichkeit einer Nierentoxizität ist bei Ifosamid größer als bei Cyclophosphamid.
Anwendung
Produkt-Nr.
Beschreibung
Preisangaben
Signalwort
Danger
H-Sätze
Gefahreneinstufungen
Acute Tox. 3 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 1B
Lagerklassenschlüssel
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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