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GW22386

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Anti-MORF4 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

chicken

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

human, mouse

Hersteller/Markenname

Genway 15-288-22386

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

NP_006783.2

UniProt-Hinterlegungsnummer

Q9Y690

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... MORF4(10934)

Immunogen

Immunogen Sequence: GI # 6996928, sequence 1-235

Anwendung

Anti-MORF4 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

Morf4 is a member of a family of seven genes and is mapped on chromosomes 15 (4q33-q34.1). It is a positive regulators of cell division and interact with histone deacetylases and acetyltransferases. Morf4 functions in regulation of chromatin dynamics. The proteins that escapes degradation in the cytoplasm, is transported to the nucleus where it is functional.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Steven D Bryce et al.
Neoplasia (New York, N.Y.), 4(6), 544-550 (2002-10-31)
Human chromosome 4 was previously shown to elicit features of senescence when introduced into cell lines that map to complementation group B for senescence, including HeLa cells. Subsequently, a DNA segment encoding the pseudogene Mortality Factor 4 (MORF4) was shown
Meizhen Chen et al.
Annals of the New York Academy of Sciences, 1197, 134-141 (2010-06-12)
Cellular senescence is the dominant phenotype over immortality. In our studies to identify senescence-related genes, we cloned Morf4, which induced senescence in a subset of tumor cells. Morf4 is a member of a family of seven genes, and Morf-related genes
Kaoru Tominaga et al.
Experimental cell research, 316(1), 92-102 (2009-09-23)
After undergoing several rounds of divisions normal human fibroblasts enter a terminally non-dividing state referred to as cellular or replicative senescence. We cloned MORF4 (mortality factor on human chromosome 4), as a cellular senescence inducing gene that caused immortal cells

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