GW21285B

Anti-AXO antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-Axotrophin variant
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: chicken
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Hersteller/Markenname: Genway 15-288-21285B
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_073737.1
• UniProt-Hinterlegungsnummer: Q53GQ1
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... MARCH7(64844)

Beschreibung

Immunogen

Immunogen Sequence: GI # 12383066, sequence 481-680

Recombinant axotrophin

Anwendung

Anti-AXO antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

E3 ubiquitin-protein ligase MARCH7 (axotrophin) is an enzyme encoded by the MARCH7 gene in humans and belongs to the MARCH family of proteins. It is a novel family of transmembrane ubiquitin ligases that target glycoproteins for lysosomal destruction via ubiquitination of the cytoplasmic tail. MARCH-7 was first identified in mouse embryonic stem cells as a neural stem cell gene. It has a distinct expression profile from that of other MARCH family members.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)