G0921

6′-GNTI -ditrifluoracetat

≥97.5% (HPLC), solid

• Synonym(e): 6′-GNTI, : [(4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,8a,9,14,14b-octahydro-1,8a-dihydroxy-4,8-methanobenzofuro[2,3-a]pyrido[4,3-b]carbazol-12-yl]-guanidine ditrifluoroacetate dihydrate
• Empirische Formel (Hill-System): C₂₇H₂₉N₅O₃ · 2CF₃CO₂H · 2H₂O
• CAS-Nummer: 35080-00-3
• Molekulargewicht: 735.63
• MDL-Nummer: MFCD09752601
• UNSPSC-Code: 12352200

Eigenschaften

• Assay: ≥97.5% (HPLC)
• Form: solid
• Lagerbedingungen: desiccated; under inert gas
• Farbe: pink to tan
• Löslichkeit: H₂O: >20 mg/mL
• Lagertemp.: −20°C
• SMILES String: O.O.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.NC(=N)Nc1ccc2c3C[C@@]4(O)[C@H]5Cc6ccc(O)c7OC(c3[nH]c2c1)[C@]4(CCN5CC8CC8)c67

Beschreibung

Biochem./physiol. Wirkung

6′-GNTI is a selective agonist of κ/δ opioid receptor heterodimers in the spinal cord and has the unique property of selectively activating only opioid receptor heterodimers and not homomers. 6′-GNT functions as an analgesic demonstrating that opioid receptor heterodimers are functionally relevant in vivo.

Vorsicht

Air-sensitive

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)