F8527

Monoclonal Anti-CD45−FITC/CD14-PE DUAL-TAG^™ antibody produced in mouse

clone BRA-55/UCHM-1, purified immunoglobulin, buffered aqueous solution

• MDL-Nummer: MFCD00213147
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: mouse
• Konjugat: FITC conjugate; phycoerythrin (R-PE) conjugate
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: BRA-55/UCHM-1, monoclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): flow cytometry: 20 μL using 1 × 10⁶ cells
• Isotyp: IgG1/IgG2a
• UniProt-Hinterlegungsnummer: P08571
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Angaben zum Gen: human ... CD14(929) , PTPRC(5788)

Beschreibung

Anwendung

Monoclonal Anti-CD45-FITC/CD14-PE DUAL-TAG^™ antibody is suitable for flow cytometry at a concentration of 20μL using 1×106 cells.

Biochem./physiol. Wirkung

CD45 is a family of single chain transmembrane glycoproteins, consisting of different isoforms, which share a common large intracellular domain. It is abundantly present in leukocyte cell surface and belongs to a novel class of enzymes, the protein tyrosine phosphatases (PTPs). It plays an essential role in thymic selection and peripheral activation of T and B cells. It is associated with various signal transduction pathways. It may also accelerate the Src family tyrosine kinases activity. an important determinant of immune tolerance.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Rechtliche Hinweise

DUAL-TAG is a trademark of Sigma-Aldrich Co. LLC

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.