E6511

Ethylendiamintetraessigsäure Tetranatriumsalz Dihydrat

BioReagent, suitable for cell culture, 98.5-102.0%

• Synonym(e): EDTA Tetranatriumsalz, Edathamil, Tetranatrium-Ethylendiamintetraacetat Dihydrat
• Lineare Formel: (NaOOCCH₂)₂NCH₂CH₂N(CH₂COONa)₂ · 2H₂O
• CAS-Nummer: 10378-23-1
• Molekulargewicht: 416.20
• Beilstein: 3861753
• EG-Nummer: 200-573-9
• MDL-Nummer: MFCD00150026
• UNSPSC-Code: 12352204
• PubChem Substanz-ID: 24894629
• NACRES: NA.75

Eigenschaften

• Produktlinie: BioReagent
• Assay: 98.5-102.0%
• Form: powder
• Methode(n): cell culture | mammalian: suitable
• Löslichkeit: H₂O: 160 mg/mL
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4
• InChIKey: KSYNLCYTMRMCGG-UHFFFAOYSA-J

Beschreibung

Allgemeine Beschreibung

Ethylenediaminetetraacetic acid (EDTA) is a chelator of metal ions.[1] It is a substituted diamine, which has antibacterial activity. EDTA removes the undesirable effects of ferric, cupric and manganic ions in bleaching. It prevents cellular division, chlorophyll synthesis and algal biomass production.[2] EDTA is an inhibitor of metalloprotease.[1] It has anticoagulant property.[3]

Anwendung

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:

• as a chelating agent to isolate human endometrial stem cell/stromal cells (hEnSCs) from menstrual blood[4]
• as a chelator in animal and testicular cell isolation[5]
• as a chelator for the culture of neural stem cells[6]

Biochem./physiol. Wirkung

Etyhlendiamintetraessigsäure (EDTA) wird zum Eliminieren der Enzymhemmung durch Schwermetallspuren sowie zur Hemmung von Enzymen, die zweiwertige Kationen als Cofaktoren benötigen verwendet.

Sicherheitshinweise

• Piktogramme: GHS08,GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302 + H332,H318,H373
• P-Sätze: P260 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Gefahreneinstufungen: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2
• Zielorgane: Respiratory Tract
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves