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Wichtige Dokumente
E3256
Edrophoniumchlorid
Synonym(e):
N-Ethyl-3-hydroxy-N,N-dimethylaniliniumchlorid
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About This Item
SMILES String
[Cl-].CC[N+](C)(C)c1cccc(O)c1
InChI
1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H
InChIKey
BXKDSDJJOVIHMX-UHFFFAOYSA-N
Angaben zum Gen
human ... ACHE(43)
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Biochem./physiol. Wirkung
Acetycholinesterase inhibitor
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Pediatric emergency care, 26(5), 374-375 (2010-05-11)
Myasthenia gravis is a rare, chronic, autoimmune disorder characterized by postsynaptic dysfunction at the neuromuscular junction. The disease affects more females than males. We describe the case of a 17-year-old female adolescent with recurrent episodes of dysarthria and dysphagia and
The Biochemical journal, 448(1), 83-91 (2012-08-15)
The principal role of AChE (acetylcholinesterase) is termination of impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine. The active site of AChE is near the bottom of a long and narrow gorge lined with aromatic residues.
Movement disorders : official journal of the Movement Disorder Society, 23(12), 1725-1732 (2008-07-29)
Patients with Parkinson's disease (PD) often have manifestations of autonomic failure. About 40% have neurogenic orthostatic hypotension (NOH), and among PD+NOH patients virtually all have evidence of cardiac sympathetic denervation; however, whether PD+NOH entails extra-cardiac noradrenergic denervation has been less
Internal medicine (Tokyo, Japan), 49(1), 69-72 (2010-01-05)
We describe a 52-year-old man with a history of increasing fatigability and gait disturbances that were first attributed to hypothyroidism. On examination, he had bilateral pseudo-internuclear ophthalmoplegia with weakness of adduction and abducting nystagmus. Convergence was also impaired and he
Muscle & nerve, 39(3), 328-332 (2009-01-08)
Demographic, clinical, and laboratory features were compared in 235 white and African-American (AA) patients with myasthenia gravis (MG) at the University of Alabama at Birmingham Neuromuscular Disease Clinic from May 2003 to January 2008. Seventy nine percent of patients were
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