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D1875
Dansyl-L-prolin
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About This Item
Empirische Formel (Hill-System):
C17H20N2O4S
CAS-Nummer:
Molekulargewicht:
348.42
Beilstein:
497317
MDL-Nummer:
UNSPSC-Code:
12352200
Lagertemp.
−20°C
SMILES String
CN(C)c1cccc2c(cccc12)S(=O)(=O)N3CCC[C@H]3C(O)=O
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Alan D Borthwick et al.
Bioorganic & medicinal chemistry letters, 12(13), 1719-1722 (2002-06-18)
Mechanism-based inhibitors of HCMV protease, which are stable to human plasma (> or = 20 h) and have single-figure potency in the microM range against HCMV protease, have been developed based on the dansylproline alpha-methyl pyrrolidine-5,5-trans-lactam nucleus.
A A Gershkovich et al.
Journal of biochemical and biophysical methods, 45(2), 183-191 (2000-09-16)
A method of conjugating protein molecules under native conditions with water-insoluble hydrophobic compounds is developed. It permits very water-insoluble acids to be gently coupled to the primary amines on proteins or other biopolymers. For this purpose we synthesized a polymer
Y Abe et al.
Biochimica et biophysica acta, 1433(1-2), 188-197 (1999-08-14)
The enantioselective binding sites on bovine serum albumin were examined by HPLC using 19 racemic 5-N, N-dimethylamino-1-naphthalenesulfonyl derivatives of alpha-amino acids (dansyl amino acids) as chiral probes. On a bovine serum albumin bonded chiral stationary phase, seven L-forms eluted faster
N Okabe et al.
Biological & pharmaceutical bulletin, 17(1), 16-21 (1994-01-01)
Binding properties of Sudlow's site-specific drugs to glycosylated human serum albumin (G-HSA) were investigated using fluorescence and circular dichroism (CD). Dansylamide, phenylbutazone and warfarin were used as site I-specific drugs, and dansylproline, ibuprofen and flufenamic acid were used as site
Yan-Min Chen et al.
Archives of toxicology, 83(3), 255-261 (2008-10-16)
Binding of five perfluoroalkyl acids with human serum albumin (HSA) was investigated by site-specific fluorescence. Intrinsic fluorescence of tryptophan-214 in HSA was monitored upon addition of the chemicals. Although perfluorobutyl acid (PFBA) and perfluorobutane sulfonate (PFBS) did not cause fluorescence
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