C2741

Anti-CCR-1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-C-C Chemokine Receptor 1
• MDL-Nummer: MFCD01864142
• UNSPSC-Code: 51111800
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Verfügbarkeit: not available in Japan
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5 μg/mL using human skeletal muscle, myocytes
• UniProt-Hinterlegungsnummer: P32246
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... CCR1(1230) ; mouse ... Ccr1(12768) ; rat ... Ccr1(57301)

Beschreibung

Immunogen

synthetic peptide corresponding to the third extracellular loop of human C-C chemokine receptor 1 (CCR-1), conjugated to KLH. The immunizing peptide has 80% homology with the rat gene and 85% homology with the mouse gene.

Biochem./physiol. Wirkung

CCR1 is a seven transmembrane protein that binds to macrophage inflammatory protein 1 alpha (MIP-1 alpha), monocyte chemoattractant protein 3 (MCP-3) and myeloid progenitor inhibitory factor-1 (MPIF-1). It has important role in protecting the host from inflammatory responses, viruses and parasites.

Physikalische Form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable