B3806

Bisindolylmaleimide VIII acetate salt

≥93% (H-NMR)

• Synonym(e): Ro 31-7549 acetate
• Empirische Formel (Hill-System): C₂₄H₂₂N₄O₂ · C₂H₄O₂
• CAS-Nummer: 138516-31-1
• Molekulargewicht: 458.51
• MDL-Nummer: MFCD00909467
• UNSPSC-Code: 12352200

Eigenschaften

• Assay: ≥93% (H-NMR)
• Löslichkeit: DMSO: soluble; H₂O: soluble; methanol: soluble
• Lagertemp.: −20°C
• SMILES String: CC(O)=O.Cn1cc(C2=C(C(=O)NC2=O)c3cn(CCCN)c4ccccc34)c5ccccc15
• InChI: 1S/C24H22N4O2.C2H4O2/c1-27-13-17(15-7-2-4-9-19(15)27)21-22(24(30)26-23(21)29)18-14-28(12-6-11-25)20-10-5-3-8-16(18)20;1-2(3)4/h2-5,7-10,13-14H,6,11-12,25H2,1H3,(H,26,29,30);1H3,(H,3,4)
• InChIKey: VEOXVBTXROWDAH-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Bisindolylmaleimide VIII acetate is a selective inhibitor of protein kinase C (PKC). Bisindolylmaleimide VIII acetate enhances Fas- and TRAIL-mediated apoptosis and inhibits T cell-mediated autoimmune diseases.

Selective inhibitor of protein kinase C. Enhances Fas- and TRAIL-mediated apoptosis and inhibits T cell-mediated autoimmune diseases.

Vorsicht

Photosensitive

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)