AV38567

Anti-NR1D2 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-BD73, Anti-EAR-1r, Anti-HZF2, Anti-Hs.37288, Anti-Nuclear receptor subfamily 1, group D, member 2, Anti-RVR
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 65 kDa
• Speziesreaktivität: rabbit, human
• Konzentration: 0.5 mg - 1 mg/mL
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_005117
• UniProt-Hinterlegungsnummer: Q14995
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... NR1D2(9975)

Beschreibung

Immunogen

Synthetic peptide directed towards the N terminal region of human NR1D2

Biochem./physiol. Wirkung

NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5′-AATGTAGGTCA-3′ and 5′-ATAACTAGGTCA-3′ and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.

Sequenz

Synthetic peptide located within the following region: YISSSSSASSHASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL

Physikalische Form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable