A9102

AH13205

≥98% (HPLC), oil

• Synonym(e): trans-2-(4-(1-Hydroxyhexyl)phenyl-5-oxocyclopentaneheptanoic acid
• Empirische Formel (Hill-System): C₂₄H₃₆O₄
• CAS-Nummer: 148436-63-9
• Molekulargewicht: 388.54
• MDL-Nummer: MFCD00797641
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329771031
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: oil
• Farbe: pale yellow
• Löslichkeit: DMSO: >10 mg/mL
• Ersteller: GlaxoSmithKline
• Lagertemp.: −20°C
• SMILES String: CCCCCC(O)c1ccc(cc1)[C@H]2CCC(=O)[C@@H]2CCCCCCC(O)=O
• InChI: 1S/C24H36O4/c1-2-3-6-10-22(25)19-14-12-18(13-15-19)20-16-17-23(26)21(20)9-7-4-5-8-11-24(27)28/h12-15,20-22,25H,2-11,16-17H2,1H3,(H,27,28)/t20-,21-,22?/m1/s1
• InChIKey: XMQKDOCUWFCMEJ-JAZPPYFYSA-N

Beschreibung

Allgemeine Beschreibung

AH13205 is EP₂ prostanoid receptor agonist. There are five types of prostanoid receptors, which are classified based on sensitivity to the five naturally-occuring prostanoid ligand. The EP type of receptor is further divided into four subgroups – EP₁, EP₂, EP₃ and EP₄. EP₂ activation results in vascular, bronchial and reproductive smooth muscle relaxation.

Biochem./physiol. Wirkung

AH13205 is a selective, low potency agonist for the EP₂ receptor. AH13205 has been shown to compete with Prostaglandin E2 (PGE2) for binding, resulting in the displacement of PGE2 binding.

Leistungsmerkmale und Vorteile

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)