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Merck

A7477

Sigma-Aldrich

Anti-ADAM-33, Catalytic Domain antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym(e):

Anti-A Disintegrin And Metalloproteinase-33

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous glycerol solution

Speziesreaktivität

human

Konzentration

~1 mg/mL

Methode(n)

western blot: 1:1,000

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... ADAM33(80332)

Allgemeine Beschreibung

A Disintegrin And Metalloproteinase-33 (ADAM-3) is a widely expressed protein that regulates cell-attachment by binding to integrins via cysteine-rich domains. ADAM-33 has also been associated with asthma susceptibility. Rabbit Anti-ADAM-33, Catalytic Domain antibody binds to the amino end of active human ADAM-33.
By immunoblotting against the reduced protein, the antibody identifies bands at 99 kDa (minor band), 58 kDa (major band), and cleaved products in cell lysates.

Immunogen

synthetic peptide corresponding to the amino end of active human ADAM-33.

Anwendung

Rabbit Anti-ADAM-33, Catalytic Domain antibody can be used for westen blot applications at 1:1,000.

Physikalische Form

Solution in phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Paul Van Eerdewegh et al.
Nature, 418(6896), 426-430 (2002-07-12)
Asthma is a common respiratory disorder characterized by recurrent episodes of coughing, wheezing and breathlessness. Although environmental factors such as allergen exposure are risk factors in the development of asthma, both twin and family studies point to a strong genetic
Tsuyoshi Yoshinaka et al.
Gene, 282(1-2), 227-236 (2002-01-30)
The ADAM family of membrane-anchored proteins has a unique domain structure, with each containing a disintegrin and metalloprotease (ADAM) domain. We have isolated mouse and human cDNAs encoding a novel member of the ADAM family. The mouse and human predicted

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